Proposal for New Classification and Practical Use of Diuretics According to Their Effects on the Serum Chloride Concentration: Rationale Based on the “Chloride Theory”

Abstract Currently, diuretic therapy for heart failure (HF) pathophysiology is primarily focused on the sodium and water balance. Over the last several years, however, chloride (Cl) has been recognized to have an important role in HF pathophysiology, as both a prognostic marker and a possible centra...

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Bibliographic Details
Main Author: Hajime Kataoka
Format: Article
Language:English
Published: Adis, Springer Healthcare 2020-05-01
Series:Cardiology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s40119-020-00172-9