A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity.

A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity.

Endogenous small molecule metabolites that regulate animal longevity are emerging as a novel means to influence health and life span. In C. elegans, bile acid-like steroids called the dafachronic acids (DAs) regulate developmental timing and longevity through the conserved nuclear hormone receptor D...

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Bibliographic Details
Main Authors: Joshua Wollam, Daniel B Magner, Lilia Magomedova, Elisabeth Rass, Yidong Shen, Veerle Rottiers, Bianca Habermann, Carolyn L Cummins, Adam Antebi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22505847/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22505847/pdf/?tool=EBI

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