Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis

Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis

Abstract Objective Therapeutic effects of focal adhesion kinase (FAK) inhibition using a small molecule inhibitor was evaluated in apolipoprotein E (apoE) knockout (KO) and low-density lipoprotein receptor (LDLr) KO mouse atherosclerosis models. Results The prevention trial consisted of an 8-week tr...

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Bibliographic Details
Main Authors: Takeshi Yamaura, Tatsuhiko Kasaoka, Naoko Iijima, Masaaki Kimura, Shinji Hatakeyama
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Research Notes
Subjects:
Atherosclerosis
Focal adhesion kinase
apoE KO
LDLr KO
Online Access:http://link.springer.com/article/10.1186/s13104-019-4220-5

Internet

http://link.springer.com/article/10.1186/s13104-019-4220-5

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