The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites

Cockayne syndrome group B protein (CSB), a member of the SWI/SNF superfamily, resides in an elongating RNA polymerase II (RNAPII) complex and regulates transcription elongation. CSB contains a C-terminal winged helix domain (WHD) that binds to ubiquitin and plays an important role in DNA repair. How...

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Bibliographic Details
Main Authors: Nicole L. Batenburg, Shixin Cui, John R. Walker, Herb E. Schellhorn, Xu-Dong Zhu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/7/3379