The role of the c-Met pathway in lung cancer and the potential for targeted therapy

Hepatocyte growth factor receptor (HGFR), the product of the MET gene, plays an important role in normal cellular function and oncogenesis. In cancer, HGFR has been implicated in cellular proliferation, cell survival, invasion, cell motility, metastasis and angiogenesis. Activation of HGFR can occur...

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Bibliographic Details
Main Authors: Martin Sattler, Rifat Hasina, Mamatha M. Reddy, Tara Gangadhar, Ravi Salgia
Format: Article
Language:English
Published: SAGE Publishing 2011-07-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834011408636