The nephroprotective effects and mechanisms of rehmapicrogenin include ROS inhibition via an oestrogen-like pathway both in vivo and in vitro

The nephroprotective effects and mechanisms of rehmapicrogenin include ROS inhibition via an oestrogen-like pathway both in vivo and in vitro

Background: The root of Rehmannia glutinosa (R. glutinosa) is commonly used in various traditional Chinese herbal formulae to ameliorate nephropathy; however, little is known about its active component(s) and mechanisms. Aim: In the present study, we examined the protective effect and potential mech...

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Bibliographic Details
Main Authors: Mengmeng Wang, Yingying Ke, Yage Li, Zengfu Shan, Wangyang Mi, Yangang Cao, Weisheng Feng, Xiaoke Zheng
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Rehmapicrogenin
CKD
Adriamycin
Oxidative stress
Nrf2/ARE
Oestrogen receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221000901

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http://www.sciencedirect.com/science/article/pii/S0753332221000901

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