Transcriptomic Analysis of Streptococcus pyogenes Colonizing the Vaginal Mucosa Identifies hupY, an MtsR-Regulated Adhesin Involved in Heme Utilization

Colonization of the host requires the ability to adapt to an environment that is often low in essential nutrients such as iron. Here we present data showing that the transcriptome of the important human pathogen Streptococcus pyogenes shows extensive remodeling during in vivo growth, resulting in, a...

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Bibliographic Details
Main Authors: Laura C. C. Cook, Nilanjana Chatterjee, Yan Li, Jorge Andrade, Michael J. Federle, Zehava Eichenbaum
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00848-19