Capsaicin Enhances the Drug Sensitivity of Cholangiocarcinoma through the Inhibition of Chemotherapeutic-Induced Autophagy.

Cholangiocarcinoma (CCA), a devastating cancer with a poor prognosis, is resistant to the currently available chemotherapeutic agents. Capsaicin, the major pungent ingredient found in hot red chili peppers of the genus Capsicum, suppresses the growth of several malignant cell lines. Our aims were to...

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Bibliographic Details
Main Authors: Zai-Fa Hong, Wen-Xiu Zhao, Zhen-Yu Yin, Cheng-Rong Xie, Ya-Ping Xu, Xiao-Qin Chi, Sheng Zhang, Xiao-Min Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416771?pdf=render