Natural presence of the V179D and K103R/V179D mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors in HIV-1 CRF65_cpx strains

Natural presence of the V179D and K103R/V179D mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors in HIV-1 CRF65_cpx strains

Abstract Background There is increasing evidence that HIV-1 genetic diversity can have an impact on drug resistance. The aim of this study is to investigate the epidemiological situation of CRF65_cpx and the impact of natural polymorphisms of this variant on genotypic resistance. Methods We used the...

Full description

Bibliographic Details
Main Authors: Yongjian Liu, Yu Zhang, Hanping Li, Xiaolin Wang, Lei Jia, Jingwan Han, Tianyi Li, Jingyun Li, Lin Li
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Infectious Diseases
Subjects:
HIV
CRF65_cpx
V179D
Drug resistance
Online Access:http://link.springer.com/article/10.1186/s12879-020-05007-5

Internet

http://link.springer.com/article/10.1186/s12879-020-05007-5

Similar Items