The roles of FADD in extrinsic apoptosis and necroptosis

The roles of FADD in extrinsic apoptosis and necroptosis

Fas-associated protein with death domain (FADD), an adaptorthat bridges death receptor signaling to the caspase cascade, isindispensible for the induction of extrinsic apoptotic cell death.Interest in the non-apoptotic function of FADD has greatlyincreased due to evidence that FADD-deficient mice or...

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Bibliographic Details
Main Author: Eun-Woo Lee1,*, Jinho Seo1, Manhyung Jeong1, Sangsik Lee2 & Jaewhan Song1,*
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-09-01
Series:BMB Reports
Subjects:
Caspase-8
FADD
Necroptosis
Programmed necrosis
RIP3
Online Access:http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS05JTVEMTIwOTI3MTUyNV8lMjg0OTYtNTA4JTI5Qk1CXzEyLTE4Ni5wZGY=

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http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS05JTVEMTIwOTI3MTUyNV8lMjg0OTYtNTA4JTI5Qk1CXzEyLTE4Ni5wZGY=

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