CCR7 expressing mesenchymal stem cells potently inhibit graft-versus-host disease by spoiling the fourth supplemental Billingham's tenet.

The clinical acute graft-versus-host disease (GvHD)-therapy of mesenchymal stem cells (MSCs) is not as satisfactory as expected. Secondary lymphoid organs (SLOs) are the major niches serve to initiate immune responses or induce tolerance. Our previous study showed that CCR7 guide murine MSC line C3H...

Full description

Bibliographic Details
Main Authors: Hong Li, Yan-Ming Jiang, Yan-Feng Sun, Ping Li, Rui-Jie Dang, Hong-Mei Ning, Yu-Hang Li, Ying-Jie Zhang, Xiao-Xia Jiang, Xi-Min Guo, Ning Wen, Yan Han, Ning Mao, Hu Chen, Yi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280136?pdf=render