Chromatin landscapes of retroviral and transposon integration profiles.

The ability of retroviruses and transposons to insert their genetic material into host DNA makes them widely used tools in molecular biology, cancer research and gene therapy. However, these systems have biases that may strongly affect research outcomes. To address this issue, we generated very larg...

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Bibliographic Details
Main Authors: Johann de Jong, Waseem Akhtar, Jitendra Badhai, Alistair G Rust, Roland Rad, John Hilkens, Anton Berns, Maarten van Lohuizen, Lodewyk F A Wessels, Jeroen de Ridder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3983033?pdf=render