Total genetic contribution assessment across the human genome

Total genetic contribution assessment across the human genome

Quantifying the effects of individual loci on the human phenome is a challenging task. Here, the authors introduce a modelling technique, TGCA, that assesses total genetic contribution per locus and apply this to UK Biobank phenotype domains, revealing top loci and links to tissue-specific gene expr...

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Bibliographic Details
Main Authors: Ting Li, Zheng Ning, Zhijian Yang, Ranran Zhai, Chenqing Zheng, Wenzheng Xu, Yipeng Wang, Kejun Ying, Yiwen Chen, Xia Shen
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23124-w

Internet

https://doi.org/10.1038/s41467-021-23124-w

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