Refolding Technology for scFv Using a New Detergent, N-Lauroyl-L-glutamate and Arginine

Monoclonal antibodies to the soluble antigens or cell surface markers hold great promise as effective human therapeutics. One of the major disadvantages is its large size, which prevents efficient penetration into the target tissues. Smaller version of antibodies, which has only antigen binding site...

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Bibliographic Details
Main Authors: Tsutomu Arakawa, Yoshiko Kita, Daisuke Ejima
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/1/2/215