Late multiple organ surge in interferon-regulated target genes characterizes staphylococcal enterotoxin B lethality.

Late multiple organ surge in interferon-regulated target genes characterizes staphylococcal enterotoxin B lethality.

BACKGROUND: Bacterial superantigens are virulence factors that cause toxic shock syndrome. Here, the genome-wide, temporal response of mice to lethal intranasal staphylococcal enterotoxin B (SEB) challenge was investigated in six tissues. RESULTS: The earliest responses and largest number of affecte...

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Bibliographic Details
Main Authors: Gabriela A Ferreyra, Jason M Elinoff, Cumhur Y Demirkale, Matthew F Starost, Marilyn Buckley, Peter J Munson, Teresa Krakauer, Robert L Danner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923834?pdf=render

Internet

http://europepmc.org/articles/PMC3923834?pdf=render

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