Risk evaluation of impurities in topical excipients: The acetol case

Pharmaceutical excipients for topical use may contain impurities, which are often neglected from a toxicity qualification viewpoint. The possible impurities in the most frequently used topical excipients were evaluated in-silico for their toxicity hazard. Acetol, an impurity likely present in differ...

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Bibliographic Details
Main Authors: Jente Boonen, Lieselotte Veryser, Lien Taevernier, Nathalie Roche, Kathelijne Peremans, Christian Burvenich, Bart De Spiegeleer
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177913001512