Dendrimers Show Promise for siRNA and microRNA Therapeutics

Dendrimers Show Promise for siRNA and microRNA Therapeutics

The lack of an appropriate intracellular delivery system for therapeutic nucleic acids (TNAs) is a major problem in molecular biology, biotechnology, and medicine. A relatively new class of highly symmetrical hyperbranched polymers, called dendrimers, shows promise for transporting small TNAs into b...

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Bibliographic Details
Main Authors: Volha Dzmitruk, Evgeny Apartsin, Aliaksei Ihnatsyeu-Kachan, Viktar Abashkin, Dzmitry Shcharbin, Maria Bryszewska
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Pharmaceutics
Subjects:
dendrimer
denderiplex
dendron
miRNA
siRNA
microRNA
antimiR
gene therapy
gene delivery
gene drugs
Online Access:http://www.mdpi.com/1999-4923/10/3/126

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http://www.mdpi.com/1999-4923/10/3/126

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