Fingolimod for Irradiation-Induced Neurodegeneration

BackgroundCranial irradiation is a common therapy for the treatment of brain tumors, but unfortunately patients suffer from side effects, particularly cognitive impairment, caused by neurodegenerative and neuroinflammatory mechanisms. Finding a therapeutic agent protecting hippocampal neurons would...

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Bibliographic Details
Main Authors: Judith Metzdorf, Zaynab Hobloss, Sibylle Schlevogt, Ilya Ayzenberg, Sarah Stahlke, Xiomara Pedreiturria, Steffen Haupeltshofer, Ralf Gold, Lars Tönges, Ingo Kleiter
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00699/full