Efficient in vivo electroporation of the postnatal rodent forebrain.

Functional gene analysis in vivo represents still a major challenge in biomedical research. Here we present a new method for the efficient introduction of nucleic acids into the postnatal mouse forebrain. We show that intraventricular injection of DNA followed by electroporation induces strong expre...

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Bibliographic Details
Main Authors: Camille Boutin, Simone Diestel, Angélique Desoeuvre, Marie-Catherine Tiveron, Harold Cremer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2270900?pdf=render