Activation of the PI3K/AKT pathway in Merkel cell carcinoma.

Activation of the PI3K/AKT pathway in Merkel cell carcinoma.

Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with an increasing incidence. The understanding of the molecular carcinogenesis of MCC is limited. Here, we scrutinized the PI3K/AKT pathway, one of the major pathways activated in human cancer, in MCC. Immunohistochemical analysis of 41...

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Bibliographic Details
Main Authors: Christian Hafner, Roland Houben, Anne Baeurle, Cathrin Ritter, David Schrama, Michael Landthaler, Juergen C Becker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281946?pdf=render

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http://europepmc.org/articles/PMC3281946?pdf=render

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