Skeletal Muscle Metabolism: Origin or Prognostic Factor for Amyotrophic Lateral Sclerosis (ALS) Development?

Skeletal Muscle Metabolism: Origin or Prognostic Factor for Amyotrophic Lateral Sclerosis (ALS) Development?

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive and selective loss of motor neurons, amyotrophy and skeletal muscle paralysis usually leading to death due to respiratory failure. While generally considered an intrinsic motor neuron disease, data...

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Bibliographic Details
Main Authors: Cyril Quessada, Alexandra Bouscary, Frédérique René, Cristiana Valle, Alberto Ferri, Shyuan T. Ngo, Jean-Philippe Loeffler
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
skeletal muscle
ALS
neuromuscular junction
hypermetabolism
PDK4
metabolic imbalance
Online Access:https://www.mdpi.com/2073-4409/10/6/1449

Internet

https://www.mdpi.com/2073-4409/10/6/1449

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