Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells.

Claudins are membrane proteins that play critical roles in tight junction (TJ) formation and function. Members of the claudin gene family have been demonstrated to be aberrantly regulated, and to participate in the pathogenesis of various human cancers. In the present study, we report that claudin-1...

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Main Authors: Rachana Agarwal, Yuriko Mori, Yulan Cheng, Zhe Jin, Alexandru V Olaru, James P Hamilton, Stefan David, Florin M Selaru, Jian Yang, John M Abraham, Elizabeth Montgomery, Patrice J Morin, Stephen J Meltzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2776495?pdf=render