Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice

Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice

<p>Very long chain fatty acids (VLCFA), either free or as components of glycerolipids and sphingolipids, are present in many organs. Elongation of very long chain fatty acids-4 (ELOVL4) belongs to a family of 6 members of putative fatty acid elongases that are involved in the formation of VLCF...

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Bibliographic Details
Main Author: Wenmei Li, Roger Sandhoff, Mari Kono, Patricia Zerfas, Vickie Hoffmann, Bryan Char-Hoa Ding, Richard L. Proia, Chu-Xia Deng
Format: Article
Language:English
Published: Ivyspring International Publisher 2007-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v03p0120.htm

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http://www.biolsci.org/v03p0120.htm

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