NsrR, GadE, and GadX interplay in repressing expression of the Escherichia coli O157:H7 LEE pathogenicity island in response to nitric oxide.

NsrR, GadE, and GadX interplay in repressing expression of the Escherichia coli O157:H7 LEE pathogenicity island in response to nitric oxide.

Expression of genes of the locus of enterocyte effacement (LEE) is essential for adherence of enterohemorrhagic Escherichia coli (EHEC) to intestinal epithelial cells. Gut factors that may modulate LEE gene expression may therefore influence the outcome of the infection. Because nitric oxide (NO) is...

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Bibliographic Details
Main Authors: Priscilla Branchu, Stéphanie Matrat, Marjolaine Vareille, Annie Garrivier, Alexandra Durand, Sébastien Crépin, Josée Harel, Grégory Jubelin, Alain P Gobert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3887101?pdf=render

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http://europepmc.org/articles/PMC3887101?pdf=render

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