Immunometabolic Effect of Cholesterol in Hepatitis C Infection: Implications in Clinical Management and Antiviral Therapy

Immunometabolic Effect of Cholesterol in Hepatitis C Infection: Implications in Clinical Management and Antiviral Therapy

Hepatitis C virus (HCV) is a lipid-enveloped virion particle that causes infection to the liver, and as part of its life cycle, it disrupts the host lipid metabolic machinery, particularly the cholesterol synthesis pathway. The innate immune response generated by liver resident immune cells is respo...

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Bibliographic Details
Main Authors: Karina González-Aldaco, Luis A. Torres-Reyes, Claudia Ojeda-Granados, Alexis José-Ábrego, Nora A. Fierro, Sonia Román
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Annals of Hepatology
Subjects:
Innate immune response
Lipid metabolism
HCV life cycle
Genetic polymorphisms
Diet
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119310531

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http://www.sciencedirect.com/science/article/pii/S1665268119310531

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