HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear

HIV-1 transcription is regulated at the level of elongation by the viral Tat protein together with the cellular elongation factor P-TEFb, which is composed of cyclin T1 and Cdk9 subunits. The crystal structure of a Tat:P-TEFb complex (Tahirov, T.H.; Babayeva, N.D.; Varzavand, K.; Cooper, J.J.; Sedor...

Full description

Bibliographic Details
Main Authors: Alan D. Frankel, Iván D’Orso
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Viruses
Subjects:
Tat
Online Access:http://www.mdpi.com/1999-4915/2/10/2226/