Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir.

In the absence of an effective vaccine, HIV continues to spread globally, emphasizing the need for novel strategies to limit its transmission. Pre-exposure prophylaxis (PrEP) with antiretroviral drugs could prove to be an effective intervention strategy if highly efficacious and cost-effective PrEP...

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Bibliographic Details
Main Authors: J Gerardo García-Lerma, Ron A Otten, Shoukat H Qari, Eddie Jackson, Mian-Er Cong, Silvina Masciotra, Wei Luo, Caryn Kim, Debra R Adams, Michael Monsour, Jonathan Lipscomb, Jeffrey A Johnson, David Delinsky, Raymond F Schinazi, Robert Janssen, Thomas M Folks, Walid Heneine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2225435?pdf=render