Multi-scale chromatin state annotation using a hierarchical hidden Markov model
The impact of chromatin structure on gene expression makes it integral to our understanding of developmental and disease processes. Here, the authors introduce a hierarchical hidden Markov model to systematically annotate chromatin states at multiple length scales, and demonstrate its utility for th...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15011 |