Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization[S]

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization[S]

Mitochondrial dysfunction has been implicated in the pathogenesis of type 2 diabetes. Identifying novel regulators of mitochondrial bioenergetics will broaden our understanding of regulatory checkpoints that coordinate complex metabolic pathways. We previously showed that Nur77, an orphan nuclear re...

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Bibliographic Details
Main Authors: Lily C. Chao, Kevin Wroblewski, Olga R. Ilkayeva, Robert D. Stevens, James Bain, Gretchen A. Meyer, Simon Schenk, Leonel Martinez, Laurent Vergnes, Vihang A. Narkar, Brian G. Drew, Cynthia Hong, Rima Boyadjian, Andrea L. Hevener, Ronald M. Evans, Karen Reue, Melissa J. Spencer, Christopher B. Newgard, Peter Tontonoz
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Journal of Lipid Research
Subjects:
Nr4a
nuclear receptor
mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520417961

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http://www.sciencedirect.com/science/article/pii/S0022227520417961

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