Human Single-Chain Antibodies That Neutralize Elastolytic Activity of <i>Pseudomonas aeruginosa</i> LasB

Human Single-Chain Antibodies That Neutralize Elastolytic Activity of <i>Pseudomonas aeruginosa</i> LasB

LasB (elastase/pseudolysin) is an injurious zinc-metalloprotease secreted by the infecting <i>Pseudomonas aeruginosa</i>. LasB is recognized as the bacterial key virulence factor for establishment of successful infection, acquisition of nutrients, dissemination, tissue invasion, and immu...

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Bibliographic Details
Main Authors: Sirijan Santajit, Thida Kong-ngoen, Manas Chongsa-Nguan, Usa Boonyuen, Pornpan Pumirat, Nitat Sookrung, Wanpen Chaicumpa, Nitaya Indrawattana
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pathogens
Subjects:
elastase
elastolytic activity
human single-chain antibody
HuscFv
<i>Pseudomonas aeruginosa</i>
LasB
Online Access:https://www.mdpi.com/2076-0817/10/6/765

Internet

https://www.mdpi.com/2076-0817/10/6/765

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