Transient focal cerebral ischemia/reperfusion induces early and chronic axonal changes in rats: its importance for the risk of Alzheimer's disease.

The dementia of Alzheimer's type and brain ischemia are known to increase at comparable rates with age. Recent advances suggest that cerebral ischemia may contribute to the pathogenesis of Alzheimer's disease (AD), however, the neuropathological relationship between these two disorders is...

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Bibliographic Details
Main Authors: Qinan Zhang, Teng Gao, Yi Luo, Xijuan Chen, Ge Gao, Xiaoqun Gao, Yiwu Zhou, Jiapei Dai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3311543?pdf=render