Characterization of monomeric intermediates during VSV glycoprotein structural transition.

Entry of enveloped viruses requires fusion of viral and cellular membranes, driven by conformational changes of viral glycoproteins. Crystal structures provide static pictures of pre- and post-fusion conformations of these proteins but the transition pathway remains elusive. Here, using several biop...

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Bibliographic Details
Main Authors: Aurélie A Albertini, Cécile Mérigoux, Sonia Libersou, Karine Madiona, Stéphane Bressanelli, Stéphane Roche, Jean Lepault, Ronald Melki, Patrice Vachette, Yves Gaudin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3285605?pdf=render