(−)-Epicatechin 3-O-β-d-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways

(−)-Epicatechin 3-O-β-d-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways

Abstract Background Davallia formosana Hayata is a herb that has been used in Chinese medicine to treat bone diseases, including arthritis, bone fractures and osteoporosis. The rhizome of D. formosana H. has been found to be rich in (−)-Epicatechin 3-O-β-d-allopyranoside (ECAP), which is considered...

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Bibliographic Details
Main Authors: Hung-Bo Hsiao, Jin-Bin Wu, Wen-Chuan Lin
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Complementary and Alternative Medicine
Subjects:
ECAP
Davallia formosana Hayata
Osteoclastogenesis
Osteoporosis
Osteoclast
RANKL
Online Access:http://link.springer.com/article/10.1186/s12906-017-1737-9

Internet

http://link.springer.com/article/10.1186/s12906-017-1737-9

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