Controlling spatiotemporal pattern formation in a concentration gradient with a synthetic toggle switch

Abstract The formation of spatiotemporal patterns of gene expression is frequently guided by gradients of diffusible signaling molecules. The toggle switch subnetwork, composed of two cross‐repressing transcription factors, is a common component of gene regulatory networks in charge of patterning, c...

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Bibliographic Details
Main Authors: Içvara Barbier, Rubén Perez‐Carrasco, Yolanda Schaerli
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20199361