Determination of residual solvents in paclitaxel by headspace gas chromatography

Abstract Background A simple and sensitive gas chromatographic method was developed and validated for the simultaneous determination of methanol, ethanol, acetone, isopropyl alcohol, dichloromethane, N-hexane, ethyl acetate, tetrahydrofuran, and N,N-diisopropyl ethyl amine in Paclitaxel. A chromatog...

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Bibliographic Details
Main Authors: Khaleel Noorbasha, Abdul Rahaman Shaik
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Online Access:https://doi.org/10.1186/s43094-021-00186-7