Effects of FTY720 on Lung Injury Induced by Hindlimb Ischemia Reperfusion in Rats

Background. Sphingosine-1-phosphate (S1P) is a biologically active lysophospholipid mediator involved in modulating inflammatory process. We investigated the effects of FTY720, a structural analogue of S1P after phosphorylation, on lung injury induced by hindlimb ischemia reperfusion (IR) in rats. M...

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Bibliographic Details
Main Authors: Liangrong Wang, Feifei Chen, Yafei Pan, Lina Lin, Xiangqing Xiong
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2017/5301312