Microenvironmental Regulation of Chondrocyte Plasticity in Endochondral Repair—A New Frontier for Developmental Engineering

The majority of fractures heal through the process of endochondral ossification, in which a cartilage intermediate forms between the fractured bone ends and is gradually replaced with bone. Recent studies have provided genetic evidence demonstrating that a significant portion of callus chondrocytes...

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Bibliographic Details
Main Authors: Sarah A. Wong, Kevin O. Rivera, Theodore Miclau, Eben Alsberg, Ralph S. Marcucio, Chelsea S. Bahney
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fbioe.2018.00058/full