NSAIDs may protect against age-related brain atrophy

NSAIDs may protect against age-related brain atrophy

The use of non-steroidal anti-inflammatory drugs (NSAIDs) in humans is associated with brain differences including decreased number of activated microglia. In animals, NSAIDs are associated with reduced microglia, decreased amyloid burden, and neuronal preservation. Several studies suggest NSAIDs pr...

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Bibliographic Details
Main Authors: Barbara B Bendlin, Lisa M Newman, Michele L Ries, Luigi Puglielli, Cynthia M Carlsson, Mark A Sager, Howard A Rowley, Catherine L Gallagher, Auriel A Willette, Andrew L Alexander, Sanjay Asthana, Sterling C Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Aging
Alzheimer's disease
Risk factors
NSAIDs
volumetric MRI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00035/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00035/full

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