Rap2B promotes angiogenesis via PI3K/AKT/VEGF signaling pathway in human renal cell carcinoma

Human renal cell carcinoma which is a highly vascular tumor is the leading cause of death from urologic cancers. Angiogenesis has a pivotal role in oncogenesis and in the viability and expansion of renal cell carcinoma. Rap2B, as a small guanosine triphosphate–binding protein of the Ras family, was...

Full description

Bibliographic Details
Main Authors: Jiehui Di, Keyu Gao, Debao Qu, Yaoyao Wu, Jing Yang, Junnian Zheng
Format: Article
Language:English
Published: IOS Press 2017-07-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317701653