Rap2B promotes angiogenesis via PI3K/AKT/VEGF signaling pathway in human renal cell carcinoma
Human renal cell carcinoma which is a highly vascular tumor is the leading cause of death from urologic cancers. Angiogenesis has a pivotal role in oncogenesis and in the viability and expansion of renal cell carcinoma. Rap2B, as a small guanosine triphosphate–binding protein of the Ras family, was...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-07-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317701653 |