Rap2B promotes angiogenesis via PI3K/AKT/VEGF signaling pathway in human renal cell carcinoma
Human renal cell carcinoma which is a highly vascular tumor is the leading cause of death from urologic cancers. Angiogenesis has a pivotal role in oncogenesis and in the viability and expansion of renal cell carcinoma. Rap2B, as a small guanosine triphosphate–binding protein of the Ras family, was...
Main Authors: | Jiehui Di, Keyu Gao, Debao Qu, Yaoyao Wu, Jing Yang, Junnian Zheng |
---|---|
Format: | Article |
Language: | English |
Published: |
IOS Press
2017-07-01
|
Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317701653 |
Similar Items
-
PI3K/AKT/mTOR pathway in Angiogenesis
by: Jayashree eKarar, et al.
Published: (2011-12-01) -
Nogo-B Promotes Angiogenesis in Proliferative Diabetic Retinopathy via VEGF/PI3K/Akt Pathway in an Autocrine Manner
by: Yuelu Zhang, et al.
Published: (2017-10-01) -
Kochia scoparia seed extract suppresses VEGF-induced angiogenesis via modulating VEGF receptor 2 and PI3K/AKT/mTOR pathways
by: Hyun-Dong Cho, et al.
Published: (2019-01-01) -
Inhibition of LY294002 in retinal neovascularization via down-regulation the PI3K/AKT-VEGF pathway in vivo and in vitro
by: Yu Di, et al.
Published: (2018-08-01) -
LRIG3 Suppresses Angiogenesis by Regulating the PI3K/AKT/VEGFA Signaling Pathway in Glioma
by: Chenghao Peng, et al.
Published: (2021-02-01)