Measurement of gene amplifications related to drug resistance in Plasmodium falciparum using droplet digital PCR

Abstract Background Copy number variations (CNVs) of the Plasmodium falciparum multidrug resistance 1 (pfmdr1), P. falciparum plasmepsin2 (pfplasmepsin2) and P. falciparum GTP cyclohydrolase 1 (pfgch1) genes are associated with anti-malarial drug resistance in P. falciparum malaria. Droplet digital...

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Bibliographic Details
Main Authors: Suttipat Srisutham, Kanokon Suwannasin, Rungniran Sugaram, Arjen M. Dondorp, Mallika Imwong
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Malaria Journal
Subjects:
Online Access:https://doi.org/10.1186/s12936-021-03659-5