Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation.

Platelet aggregation is heritable, and genome-wide association studies have detected strong associations with a common intronic variant of the platelet endothelial aggregation receptor1 (PEAR1) gene both in African American and European American individuals. In this study, we used a sequencing appro...

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Bibliographic Details
Main Authors: Yoonhee Kim, Bhoom Suktitipat, Lisa R Yanek, Nauder Faraday, Alexander F Wilson, Diane M Becker, Lewis C Becker, Rasika A Mathias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660448?pdf=render