Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model

<p>Abstract</p> <p>Background</p> <p>Although increasing evidence has indicated that brain insulin dysfunction is a risk factor for Alzheimer disease (AD), the underlying mechanisms by which insulin deficiency may impact the development of AD are still obscure. Using a...

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Bibliographic Details
Main Authors: Teng Wei-Ping, Wang Si-Ling, Wang Tao, Xie Jing-Wei, Zheng Wei, Wang Xu, Wang Zhan-You
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/46