Anti-inflammatory treatment in oxygen–glucose-deprived hippocampal slice cultures is neuroprotective and associated with reduced cell proliferation and intact neurogenesis

Anti-inflammatory treatment in oxygen–glucose-deprived hippocampal slice cultures is neuroprotective and associated with reduced cell proliferation and intact neurogenesis

Increased neurogenesis in response to brain injury is considered a mechanism of regeneration after neuronal loss. Using organotypic hippocampal cultures (OHC), we investigated the interplay between neuronal damage (propidium iodide uptake), microglia activation (OX-42 immunohistochemistry), cell pro...

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Bibliographic Details
Main Authors: Olga Chechneva, Klaus Dinkel, Fabio Cavaliere, Monica Martinez-Sanchez, Klaus G. Reymann
Format: Article
Language:English
Published: Elsevier 2006-08-01
Series:Neurobiology of Disease
Subjects:
Organotypic hippocampal slice cultures
Oxygen–glucose deprivation
Microglia
Inflammation
Cell damage
Cell proliferation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000544

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http://www.sciencedirect.com/science/article/pii/S0969996106000544

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