Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris

Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris

Abstract Background The antimicrobial peptide LL37 is produced by white blood cells (mainly neutrophils) and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing chemotaxis of immune cells and promoting wound healing. However, the central domain...

Full description

Bibliographic Details
Main Authors: Na Zhan, Licong Zhang, Hong Yang, Yalan Zheng, Xinke Wei, Jiajun Wang, Anshan Shan
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Microbial Cell Factories
Subjects:
Antimicrobial peptide
LL37
Pichia pastoris
Dimeric
Fusion expression
Online Access:https://doi.org/10.1186/s12934-021-01635-x

Internet

https://doi.org/10.1186/s12934-021-01635-x

Similar Items