Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury.

Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury.

Gentamicin nephrotoxicity is one of the most common causes of acute kidney injury (AKI). Hypoxia-inducible factor (HIF) is effective in protecting the kidney from ischemic and toxic injury. Increased expression of HIF-1α mRNA has been reported in rats with gentamicin-induced renal injury. We hypothe...

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Bibliographic Details
Main Authors: Jeong-myung Ahn, Sun Jin You, Yun-Mi Lee, Se-Won Oh, Shin-young Ahn, Sejoong Kim, Ho Jun Chin, Dong-Wan Chae, Ki Young Na
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3493596?pdf=render

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http://europepmc.org/articles/PMC3493596?pdf=render

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