Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation.

Antigen derived from engulfed apoptotic cells can be cross-presented by dendritic cells (DCs) for the generation of major histocompatibility class I/peptide complexes. While the early events of recognition and internalization of the dying cell have been characterized, the antigen-processing pathway...

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Bibliographic Details
Main Authors: Nathalie E Blachère, Robert B Darnell, Matthew L Albert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1084338?pdf=render