Alteronol Enhances the Anti-tumor Activity and Reduces the Toxicity of High-Dose Adriamycin in Breast Cancer

Alteronol Enhances the Anti-tumor Activity and Reduces the Toxicity of High-Dose Adriamycin in Breast Cancer

The first-line chemotherapy drug adriamycin (ADM) is widely used for the treatment of breast cancer, but the acquired drug resistance and the normal tissue toxicity remain clinical challenges. Alteronol has been reported to exert wide-ranging anti-tumor activity. In this study, we firstly examined t...

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Bibliographic Details
Main Authors: Boxue Ren, Lei Ye, Jianwei Gong, Huanhuan Ren, Yangfang Ding, Xiaoyu Chen, Xiaona Liu, Peng Lu, Fei Wei, Wenjuan Xu, Qiusheng Zheng, Defang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
alteronol
adriamycin
breast cancer
cell cycle arrest
apoptosis
chemotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00285/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00285/full

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