Efficient Suppression of Abdominal Aortic Aneurysm Expansion in Rats through Systemic Administration of Statin-Loaded Nanomedicine

Efficient Suppression of Abdominal Aortic Aneurysm Expansion in Rats through Systemic Administration of Statin-Loaded Nanomedicine

Abdominal aortic aneurysm (AAA) is a life-threatening disease. However, no systemically injectable drug has been approved for AAA treatment due to low bioavailability. Polymeric micelles are nanomedicines that have the potential to improve therapeutic efficacy by selectively delivering drugs into di...

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Bibliographic Details
Main Authors: Natsumi Fukuhara, Yuto Honda, Nao Ukita, Makoto Matsui, Yutaka Miura, Katsuyuki Hoshina
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
abdominal aortic aneurysm
drug delivery
polymeric micelle
statin
Online Access:https://www.mdpi.com/1422-0067/21/22/8702

Internet

https://www.mdpi.com/1422-0067/21/22/8702

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